Bioimpendance Neuronal Micro-stimulation (BNM) was engineered to treat sports injury and muscle atrophy, as well as promote lipolysis and muscle hypertrophy. A clinical study with individuals presenting abnormally clumped RBCs was completed in February 2009 with the Ion Magnum. Results indicate that this technology rapidly and efficiently leads to normalized erythrocytes’ separation at the microscopic level. Red Blood Cells’(RBCs) separation is crucial for the timely transport of hormones,antibodies, oxygen and nutrients to the cells and waste products to the kidneys. Therefore, blood separation is crucial in a number of biological processes including cellular cleansing, nourishment and oxygenation, endocrine and immune functioning. Ion Magnum’s (IM) dynamic, multi-sine, analogue waveform was originally tested at the cellular level by Dr. Donald Gilbert (1992), a molecular biologist, and was electronically composed by the Co-Inventor of the first Pacemaker (2008) to resonate at the motor nerve the signal of strenuous exercise normally emitted by the brain. Due to its resonance with the biological signal, the Ion Magnum signal spreads throughout the CNS ultimately triggering hormonal secretion such as Growth Hormone (GF), Thyroxine (T4) and Triiodothyronine (T3) for lipolysis and Insulin Growth Factor (IGF-1) for muscle hypertrophy. Power detox is an additional benefit of Ion Magnum’s induced effortless and painless isometric and isotonic muscle contractions. Sever al devices stimulate the muscles such asTENS Muscle Stimulators. However, TENS devices deplete ATP. Besides, muscle stimulation does not automatically release hormones. Neuronal synapses activated out of sync with the other inputs to the neuron stands out as odd and are eliminated. Neuronal synapses that are activated in sync with other inputs to the neuron are strengthened. The signal of a device must be in sync with the biological choreography in order to spread via the spinal cord and reach the brain. In sync, or resonance, has been touted by a number of approximate hit-ormiss techniques involving magnetic and electrical fields with dubious inconsistent results. But no technology has ever achieved nerve signaling that is biologically comparable to physical exercise. What the Co-Inventor of the first Pacemaker has accomplished, first in London University and then in the EU funded Research Center for Innovations Science, UK, is a full force, high-speed workout without actual movement, side effects or pain, that enhances hormonal secretion. Lipolysis and muscle hypertrophy following IM treatments has been reported by a number single subject design clinical studies.
Sunday, March 27, 2011
Healthy Blood Vessels May Prevent Fat Growth. Xanya Sofra Weiss
ScienceDaily (Sep. 23, 2008) — The cells lining blood vessels are known to be important for maintaining health, but researchers at the Indiana University School of Medicine believe these cells may perform an unsuspected task – controlling the development of fat cells.
Their findings are reported in the September issue of the journal Stem Cells.
The researchers found that precursor or stem cells have a markedly reduced tendency to develop into fat cells when placed in direct contact with healthy endothelial cells, which are the cells that line blood vessels.
"The key to this discovery was our recent observation that these cells, also known as adipose stromal cells, in fat tissue are in very close contact with endothelial cells in small blood vessels and capillaries," said Keith L. March, M.D., Ph.D., co-principal investigator of the study and director of the Indiana Center for Vascular Biology and Medicine (ICVBM).
"Once we had recognized this link between endothelial and stromal cells, it was a logical step to ask how these cells can influence each other," said Dr. March, who also is a professor of medicine, physiology and biomedical engineering at the IU School of Medicine and Krannert Institute of Cardiology.
Dr. March and his colleagues are researching uses for one of nature's building blocks, adipose stem cells, which they harvest from fat tissues. Their research looks at ways to treat vascular disease, including the use of adipose stem cells to grow new vessels as a treatment for peripheral artery disease.
When the adipose stem cells were mixed with endothelial cells, they were less likely to develop into fat cells, said Gangaraju Rajashekhar, Ph.D., lead author of the journal article and a research associate at the Indiana Center for Vascular Biology and Medicine.
What we discovered was that endothelial cells released proteins – including Wnt proteins to be precise – that play a significant role in blocking fat cell development. Wnt proteins regulate development and differentiation in many tissues and may even play a role in aging," said Dr. Rajashekhar.
The researchers cautioned that more studies are needed to determine whether repair of unhealthy endothelial cells also can help to control fat growth.
"We know now that endothelial cells in blood vessels cells help tell adipose stem cells what to do," said Matthias Clauss, Ph.D., an ICVBM co-principal investigator of the study and an associate professor for cellular and integrative physiology at the IU School of Medicine.
"What we don't know yet is how the formation of fat cells influences the blood vessel lining cells. Our current hypothesis is that endothelial dysfunction promotes fat cell development, accompanied by new blood vessel growth. We hope to soon be able to interrupt this cycle," said Dr. Clauss.
This research may result in new options for treatment of cardiovascular diseases and also could provide physicians with another weapon in the war on obesity.
Xanya Sofra Weiss
Using Quantum Medicine to Unravel Stressors That Provoke Carcinogenesis. Xanya Sofra Weiss
Human Adipose Tissue Blood Flow and Micromanipulation of Human Subcutaneous Blood Flow. Xanya Sofra Weiss
Diabetic Peripheral Neuropathy. Xanya Sofra Weiss
O B J E C T I V E— To evaluate the efficacy of combining electrotherapy with amitriptyline for the management of chronic painful peripheral neuropathy in patients with type 2 diabetes. RESEARCH DESIGN AND METHODS— Patients (n = 26) with peripheral neuro p athy were treated with amitriptyline. After 4 weeks, those patients (n = 23) who failed to re s p o n d to amitriptyline or who only had partial relief were randomized between a sham tre a t m e n t g roup (control) or an electrotherapy group. Transcutaneous electrotherapy was given for 12 weeks by a portable unit (H-wave machine) that generated a biphasic exponentially decaying w a v e f o rm (pulse width 4 ms, 25–35 V, 2 Hz). The degree of pain and discomfort was graded on a scale of 0–5. An analog scale was used to re c o rd the overall change in symptoms.
R E S U LT S— Amitriptyline produced some degree of symptomatic relief in 15 (60%) of the 26 patients by the 4th week; pain scores decreased from 3.8 ± 0.1 to 2.9 ± 0.2 (P 0.1) and the overall reduction in pain was 26 ± 5% on an analog scale. In the amitriptyline plus sham treatment group (n = 9), pain scores declined from 2.8 ± 0.3 to 1.9 ± 0.5 (P 0.03) and the overall reduction in pain was 55 ± 12%, suggesting a pro c e d u re - related placebo effect. In the group receiving combined electrotherapy and amitriptyline (n = 14), symptomatic impro v ement occurred in 12 (85%) patients. Five (36%) of the patients in this group became asymptomatic. Pain scores declined from 3.2 ± 0.2 to 1.4 ± 0.4 (P 0.01) and the overall re d u c t i o n in pain was 66 ± 10%. The degree of reduction in pain scores and the incremental relief (above the amitriptyline effect) were significantly greater (P 0.03) with electrotherapy as compare d with sham treatment. The outcomes indicate a substantial beneficial effect of electro t h e r a p y over and above any placebo influ e n c e . C O N C L U S I O N S— Our clinical observations suggest that transcutaneous electrotherapy is effective in reducing the pain associated with peripheral neuro p a t h y. This form of therapy may be a useful adjunctive modality when it is combined with a pharmacological agent, such as amitriptyline, to augment symptomatic re l i e f .
Xanya Sofra Weiss
Changes in Skeletal Muscle Size and Glucose Tolerance With Electrically Stimulated Resistance Training in Subjects With Chronic Spinal Cord Injury
Abstract: Mahoney ET, Bickel CS, Elder C, Black C, Slade JM, Apple Jr D, Dudley GA.
Changes in skeletal muscle size and glucose tolerance with electrically stimulated
resistance training in subjects with chronic spinal cord injury.
Objective: To determine the effect of residence-based, resistance exercise training (RET) on affected skeletal muscle size and glucose tolerance after long-standing, complete spinal cord injury (SCI).
Design: Before-after trial.
Setting: University laboratory trial.
Participants: Five men with chronic, complete SCI (C5-T9).
Intervention: Magnetic resonance images of the thighs and an oral glucose tolerance test were performed before and after RET. Subjects performed RET with both thighs, 2d/wk Abstract Article Figures/Tables References Calorie restriction initiated at middle age improved gl... Experimental Gerontology MECHANISMS OF THROMBOSIS IN SPINAL CORD INJURY Hematology/Oncology Clinics of North America Index Exercise Physiology in Special Populations Cardiovascular Health and Fitness in Persons with Spina... Physical Medicine and Rehabilitation Clinics of North A... Poster 26 assessment of plantarflexor muscle size using... Archives of Physical Medicine and Rehabilitation
Home Browse Search My Settings Alerts Help About ScienceDirect | Contact Us | Information for Advertisers | Terms & Conditions | Privacy Policy Copyright © 2010 Elsevier B.V. All rights reserved. ScienceDirect® is a registered trademark of Elsevier B.V. for 4 sets of 10 unilateral, dynamic knee extensions for 12 weeks. Neuromuscular electric stimulation induced RET by activating the knee extensors.
Main Outcome Measures: Quadriceps femoris muscle cross-sectional area (CSA), plasma glucose, and insulin concentrations were measured before and after RET.
Results: Skeletal muscle CSA increased by 35% in the right quadriceps femoris (from
32.6cm2 to 44.0cm2) and by 39% in the left quadriceps femoris (from 34.6cm2 to
47.9cm2) as a result of training (P<.05). There were no significant changes in blood glucose or insulin after training. However, a trend for a reduction in plasma glucose levels was observed (P=.074).
Xanya Sofra Weiss
A STUDY TO DETECT THE EFFICACY OF MICRO-CURRENT THERAPY ON PESSURE ULCERS. Xanya Sofra Weiss
M. O. Ullah; 2007
Pressure ulcers (PU) are common international afflictions that occur in many different
healthcare settings. The aim of this prospective, randomized, multi-center study was to determine the
effectiveness of micro-current (MCT) therapy on patients with four chronic stages under The National
Pressure Ulcer Advisory Panel (NPUAP). PU on 60 male and female patients enrolled from 6 hospitals.
The analysis reveals that MCT has a significant effect on wound healing. Data analysis also reveals that
wounds of female patients are healed significantly faster than those of male patients and that age
significantly influenced wound healing.
Xanya Sofra Weiss
Tuesday, March 15, 2011
Live Blood Analysis. Xanya Sofra Weiss
Through a live blood analysis, you can see the life gifting element of your body come alive - your blood. After your health practioner takes one small drop of blood and places it on the slide, you observe as your blood reveals nutritional deficiencies, hormonal imbalances, yeast overgrowths, digestive problems, metal toxicity, liver stress, bacteria and parasite levels. The mysteries of your health become revealed and through the 45 minute assessment provided from your practitioner, you learn how to clean your blood and become an active participant in correcting any areas of concern. In partnership with your practitioner, you establish a proactive nutritional plan that will put you back in control of your own health
Xanya Sofra Weiss
Carpal Tunnel Supplements. Xanya Sofra Weiss
Just inside your wrist is a narrow, bony passage called the carpal
tunnel. Anything but empty, this tunnel contains nine tendons as well
as a nerve called the median nerve, all of which are encased,
sausage-like, in a slippery sheath called the synovium. When the
synovium and tendons become inflamed and swollen, they squeeze the
median nerve, which runs to the fingers.
Ever watch a live
electrical wire rub metal? The pinched median nerve can send angry
sparks of pain, numbness and tingling from your fingertips to your
shoulder. More often the pain is in the thumb and the index and middle
fingers. Sometimes the ring finger is also involved. Many people who
suffer from CTS say it feels like their hands have fallen asleep;
others complain of weak grips and stiff fingers.
Women seem to
suffer from CTS more often than men. Changes in female hormones caused
by pregnancy, taking birth control pills and menopause somehow make the
synovium swell. And because women generally have small wrists, just a
little swelling is enough to cause carpal tunnel pain, experts say.
Surgeons agree that CTS should not be treated with surgery during pregnancy. Studies by Dr. Ellis found that vitamin B6
helped relieve CTS in 11 percent of the pregnant women with severe CTS
signs and symptoms during their pregnancies. These women were treated
with 50 to 300 milligrams of B6 daily for at least 60 to 90
days before giving birth. And there was no harm to either the mother or
the child. If you'd like to try this therapy, you should discuss it
with your doctor.
Obesity creates a similar situation. "There
is about a fivefold increase in CTS in people who are obese and couch
potatoes. So we encourage them to be in better shape and lose weight,"
says Morton Kasdan, M.D., clinical professor of plastic surgery at the
University of Louisville in Kentucky and clinical professor of
preventive medicine and environmental health at the University of Kentucky in Lexington.
CTS has also become the unofficial health complaint of the modern age,
the result of an increase in cases among people in manufacturing jobs.
Officials at the U.S. Bureau of Labor Statistics don't keep records of
the number of CTS cases reported each year. Between 1986 and 1992,
cases of "repetitive trauma disorders" (a category that includes CTS
and similar conditions) zoomed from 50,000 to 282,000.
Another
common culprit is working on a computer, which doesn't require you to
take frequent breaks, as changing paper in a typewriter would. "The
repetitive activity produces inflammation, and this leads to swelling,"
explains Dr. Tunell. "That's a major contributor for the patients I
see."
| Food Factors The Hold the reins on cocktails. Drop those pounds. |
| Prescriptions for Healing Many doctors recommend B vitamins for carpal tunnel syndrome. Because even the foods richest in vitamin B6, such as bananas, avocados, brewer's yeast and beef, provide barely a single milligram of B6, you'll probably need to take a supplement. B-complex capsules often include all of the recommended vitamins. Nutrient Daily Amount Biotin 300 micrograms Riboflavin 25 milligrams Vitamin B6 50-200 milligrams MEDICAL ALERT: Take vitamin B6 in amounts above 100 milligrams only under the supervision of your doctor. |
The Benefits of B6
Doctors are divided on why vitamin B6 seems to provide relief from CTS.
The author of five published studies that demonstrate the benefits of vitamin B6 for CTS, Dr. Ellis contends that synovium swelling and inelasticity are caused by a B6 deficiency.
Dr. Ellis and Karl Folkers, D.Sc., Ph.D., professor and director of the
Institute for Biomedical Research at the University of Texas at Austin,
once healed 22 of 23 people with CTS just by giving them 50 to 300
milligrams of vitamin B6 daily for at least 12 weeks. And a number of them had already undergone surgery without experiencing relief. "Vitamin B6 is as important to your body as oxygen and water, only it takes a little longer to show the benefits," says Dr. Ellis.
The average diet, Dr. Ellis says, provides only about 1.4 milligrams of vitamin B6
a day, in part because the nutrient is lost in processing, so many
people are just not getting enough. "Raw foods are the best sources,
because heat destroys it," he says. Foods containing B6 include potatoes, bananas, chicken breast, top round of beef, fish, brown rice and avocados.
Other doctors believe vitamin B6
acts as a diuretic, helping the body to eliminate excess fluid. "During
pregnancy, your feet swell, your hands swell, rings don't fit anymore.
You're retaining fluid, especially in the wrists," says Dr. Tunell. For
some women, the problem worsens when they lie down, as fluid that makes
the ankles swell during the day is redistributed throughout the body,
including to the wrists, he says. "B6 helps you get rid of the extra water gain that's causing carpal tunnel," he says.
Another theory, backed up by two European studies, suggests that vitamin B6 somehow short-circuits an angry nerve's ability to transmit pain signals. "We don't know the mechanism, but we do know B6
reduces the amount of pain that animals feel, and that may be what's
happening here," says Allan L. Bernstein, M.D., chief of neurology at
Kaiser Permanente Medical Center in Hayward, California.
Medical experts do agree on one thing: No matter how vitamin B6
gets the job done, you have to be careful not to take too much. In
studies using laboratory animals, researchers found that excess B6 can harm your central nervous system.
Researchers at the U.S. Department of Agriculture Western Human Nutrition Research Center in San Francisco fed 12 experimental animals 1, 10, 100, 200 or 300 times their requirement of vitamin B6 for seven weeks. At the three highest levels of B6 intake, the animals' reaction time to a loud noise was reduced. Signs of a B6 overdose also include an oversensitivity to sunlight, which produces a skin rash and numbness.
"Vitamin B6 toxicity symptoms are rarely seen in healthy individuals. Moderate supplementation of B6 will not cause that kind of thing," says Robert A. Jacob, Ph.D., research chemist in micronutrients at the Western Human Nutrition
Research Center. "You'd have to megadose on it. So I don't think that
would happen if you take just a multivitamin/mineral supplement with B6 or even a 50- or 100-milligram B6 supplement. It appears only when you chronically take massive amounts."
Doctors recommend 50 to 200 milligrams of vitamin B6 daily to treat carpal tunnel.
Some Recommend Riboflavin and Biotin
There's some evidence that vitamin B6
won't work properly unless you're getting adequate amounts of
riboflavin and biotin, other B vitamins. "Each one of these vitamins is
synergistic; each works in concert with the other," says Flora Pettit,
Ph.D., a research scientist at the Biochemical Institute at the
University of Texas at Austin. Doctors suggest aiming for 300
micrograms of biotin and 25 milligrams of riboflavin daily.
By
law, most cereals, flours and other grain products are fortified with
riboflavin; milk, yogurt and cheeses are good sources, too. Biotin is
found in brewer's yeast, soy flour, cereals, egg yolks, milk, nuts and
vegetables.
Older adults, alcoholics and those with nutritionally poor diets
are at particular risk for deficiencies in these vitamins, says Dr.
Tunell. "Generally, the elderly have poor diets, and they have trouble
absorbing B vitamins anyway," says Dr. Tunell. "So they couldn't go
wrong with a B-complex supplement unless they have Parkinson's disease.
In that case, vitamin B6 may interfere with the absorption of their levodopa medication."
"My patients are getting between 50 and 100 milligrams of vitamin B6 and riboflavin a day, using a B-complex supplement," says Dr. Kasdan. "And 60 percent of them have gotten better."
Most doctors agree that catching CTS early is a key to successful treatment. "If you have severe carpal tunnel, the vitamin B6
isn't really going to reverse it," says Dr. Bernstein. "But if you
catch it early, when you're just starting to have pain and tingling,
and if there's no weakness and it bothers you at night but not during
the day, you'll do extremely well."
http://xanya-sofra-weiss.palaweb.com/info-xanya_sofra_weiss-nanotechnology
Xanya Sofra Weiss
Spatial-Temporal Structures of Human Alpha Rh ythms: Theory, Microcurrent Sources, Multiscale Measurements, and Global Binding of Local Networks.
Paul L. Nunez, Brett M. Wingeier, and Richard B. Silberstein; 2001
Abstract: A theoretical framework supporting experimental measures of dynamic properties of human
EEG is proposed with emphasis on distinct alpha rhythms. Robust relationships between measured
dynamics and cognitive or behavioral conditions are reviewed, and proposed physiological bases for EEG
at cellular levels are considered. Classical EEG data are interpreted in the context of a conceptual
framework that distinguishes between locally and globally dominated dynamic processes, as estimated
with coherence or other measures of phase synchronization. Macroscopic (scalp) potentials generated by
cortical current sources are described at three spatial scales, taking advantage of the columnar structure
of neocortex. NewEEG data demonstrate that both globally coherent and locally dominated behavior can
occur within the alpha band, depending on narrowband frequency, spatial measurement scale, and brain
state. Quasi-stable alpha phase structures consistent with global standing waves are observed. At the
same time, alpha and theta phase locking between cortical regions during mental calculations is demonstrated,consistent with neural network formation. The brain-binding problemis considered in the context of EEG dynamic behavior that generally exhibits both of these local and global aspects. But specific
experimental designs and data analysis methods may severely bias physiological interpretations in either
local or global directions.
Xanya Sofra Weiss
Nanocurrent for Aesthetics and Anti -Aging. Xanya Sofra Weiss
Xanya Sofra-Weiss
Aging is not just the sum total of individually deteriorating cells, shortened telomeres, denatured proteins and DNA molecules, or oxidative damage in the mitochondria. Aging is the dynamic process of increasing imbalances caused by: (1) cellular energy shortage, (2) incomplete cellular differentiation, (3) immune deficiency, (4) decreased systemic intelligence reflected in a/ defects in repair mechanisms, b/ inadequate spatial orientation and c/ poor network communication. International research has repeatedly shown that: (1)Electrons stabilize free radicals (2) Electron transport within DNA deflects oxidative damage; (3)Electrons provide a) direction information b) embryonic development c) cellular differentiation d) healing.(4) Electron transport chain results in Protons spinning the ATP-synthase in the mitochondria to produce ATP. Additionally, Proteins, the central intelligence mechanism of the cell are synthesized by aminoacids that are bound by virtue of their electric charge. A number of studies have shown that Protein synthesis occurs at specific frequencies below 1 Hz. Modern electronics and molecular biology research are combined to deduce the specifications for a technology that promotes Healthy Anti-aging. Resonating the firings, spatial organization and rhythms of electrically excitable cells leads to healing and rejuvenation in a completely safe, noninvasive method. However, to date, few devices pay attention to waveform formation that reflects the essence of cellular communications. There is a lot to be gained by developing a device that can emit signals capable of intertwining with those of signal transduction receptors (including G proteins, gene transcription and the activation of T cells). Such a device will not only become the protagonist in Anti-aging but it will have sufficient sophistication to heal disease and enhance overall immune efficiency.
Xanya Sofra Weiss
Sunday, March 6, 2011
Ultra-Low Microcurrent Therapy: A Novel Approach for Treatment of Chronic Resistant Wounds. Xanya Sofra Weiss
Bok Y. Lee, Keith Wendell, Noori Al-Waili, Glenn Butler ; 2007
This study was undertaken to investigate the efficacy of ultra-low microcurrent delivered by the Electro Pressure Regeneration Therapy (EPRT) device for the man- agement of chronic wounds. In this study, 23 patients with chronic skin ulcers and 2 with abdominal dehiscence that was present for an average of 16.5 mo, who were not responsive to standard conservative treatment in a hospital setting, were treated with the EPRT device. Wounds were treated with direct current (maximum
of 3 mA) of 1 polarity for 11.5 min and then with a current of the opposite polar- ity for another 11.5 min. Treatment was applied through ultra-low microcurrents (in the mA to nA range) conducted through special wraps applied above and below the wound. The results revealed that 34.8% of cases achieved complete wound healing after an average of 45.6 h of treatment, and 39.1% achieved ≥50% healing after an average of 39.7 h of treatment. Several patients achieved signifi- cant results after 1 to 2 treatments. The EPRT device not only accelerated healing
but also appeared to negate the effect of a person’s age on wound healing.
Xanya Sofra Weiss
Comparison of Apoptosis and Terminal Differentiation: The Mammalian Aging Process. Xanya Sofra Weiss
C.E. Gagna, H.-R. Kuo, E. Florea, W. Shami, R. Taormina, N. Vaswani, M. Gupta, R.Vijh, and W.C. Lambert; 2001
Apoptosis is the ordered chain of events that lead to cell destruction. Terminal differentiation (denucleation) is the process in which cells lose their nuclei but remain functional. Our group examined cell death in three tissues using two different fixatives and a postfixation procedure, involving young (5 months) and old (2 years) guinea pigs. The data reveal that B-DNA and Z-DNA content decreases, whereas single-stranded (ss-) DNA increases, in older tissues undergoing apoptosis (skin and cornea) and terminal differentiation (ocular lens). We speculate that some of the factors that contribute to the aging process might also be responsible for the enhanced amount of damaged DNA in older tissues undergoing cell death. (J Histochem 49:929–930, 2001)
Xanya Sofra Weiss
Ionic Anti-aging Solutions for Rejuvenation and Obesity. Xanya Sofra Weiss
Xanya Sofra-Weiss, Ph.D
Abstract:
The aging process cannot be conceptualized by examining a single gene or a single pathway, but can best be addressed at the systems level. Aging is not only the sum total of shortened telomeres, denatured proteins and DNA molecules, or oxidative damage in the mitochondria. Aging attacks key regulatory nodes crucial for the biological network stability. It is the dynamic process of increasing imbalances in the systemic organization of degenerating biological processes. DNA and stem cells engineering have successfully reversed certain individual components of time attrition resulting in rejuvenation and aging delay. So far, research has merely followed a sequential process that goes from the part to the whole, identifying aging genes and engineering stem cells, etc. However, discovering pieces of the puzzle still requires identification of the interconnections between matching pieces before the solution emerges. The old, the ill, and the injured all suffer from misarranged patterns of atoms. A single substitution an A for a G in a DNA molecule can cause a significant change in the conductance of the molecule leading to cancer. Such research findings demonstrate how the sequence and interrelations of amino acids in a protein, or the sequence of base pairs in a DNA molecule can become determining factors between health and disease, aging and youth. The DNA sequence alone doesn't determine everything. The importance of the spatial organization or nuclear architecture in regulating gene expression begs for scientific observation that does not merely focus on the study of atoms and molecules, (the basic components of a Gestalt); but on the interrelations, sequence, orientation and spatial organization of these atoms and molecules (the dynamic whole or Gestalt). Recent research has shown that DNA, proteins, cells, including stem cells, appear to be electrical in that they demonstrate conductivity or the presence of ionic currents. Since electricity is a dynamic entity emerging out of the interactions of atoms and molecules, we propose that perhaps the simplest way of focusing on the entire system is by decoding the complex electrical signals that map biological interactions with respect to spatial organization. Biological signals must be analyzed in terms of their amperage, frequency, voltage, interactions, orientation, spatial organization. Next will be their translation into electronic signals that comply with the specifications of amperage, frequency, voltage or biological signals. Electronic signals will then be intertwined to orchestrate a Gestalt waveform built on the basis of information attained from observations of biological interactions and architecture – a process similar to that done in Pollock’s lab (1990-2004). This Gestalt waveform will act as an electronic diplomat to awaken biological processes that have diminished with aging or disease by signaling the recuperation and activation of biological reparative mechanisms leading to extended longevity.
A clinical study with individuals presenting abnormally clumped Red Blood Cells’ (RBCs) was completed in February 2009 with a device representing the Pacemaker Technology for the Skeletal muscle. Results indicate that this technology rapidly and efficiently leads to normalized erythrocytes’ separation at the microscopic level. RBCs separation is crucial for the overall blood flow and timely transport of hormones, antibodies, oxygen and nutrients to the cells, and waste products to the kidneys. Transport of Hormones is a crucial process lipolysis (T3 and Growth Hormone -- GF) and muscle hypertrophy (Insulin Growth Factor - IGF-1). Additionally, erythro cyte separation resulting from treatment with the Pacemaker Technology appears to have a negative correlation with the number of fungal forms, poikilocytosis, thrombocyte aggregation and bac teria present in the blood prior to treatments. In summary, the erythrocyte separation resulting from treatments with the Pacemaker Thechology enhances hormonal transport including T3 and GH leading to lipolysis and muscle hypertrophy; 2) RBC;s separation enhances overall level of health by a significant reduction of free radicals. bacteria, fungal forms. etc.; 3) Obesity is characterized by reduced blood flow. The Pacemaker Thechology increases RBC’s separation resulting in normalized blood flow. In conclusion, re-establishing normal levels of blood flow will not only help reduce obesity but it will help reduce the risk of heart attack as well as all other disorders associated with obesity. Due to its resonance with the biological signal and following the rule of reinforced synapses when signals are in synch with the CNS, the signal of the Pacemaker Technology spreads throughout the CNS inducing effortless and painless isometric and isotonic muscle contractions. The Pacemaker Technology signal to the nerve ultimately triggers hormonal secretion such as Growth Hormone (GF), Thyroxine (T4) and Triiodothyronine (T3) for lipolysis and Insulin Growth Factor (IGF-1) for muscle hypertrophy.
Xanya Sofra Weiss
THYROID HORMONES IN NON-INSULIN-DEPENDENT DIABETES BEFORE AND AFTER DIETARY TREATMENT. Xanya Sofra Weiss
M. C. SHEPPARD, D. B. RAMSDEN ; 1983
In a group of 8 moderately obese non-insulin-dependent diabetics, both serum total T3 and T4 concentrations and serum free T3 and T4 concentrations were significantly lower than control values. Serum TBG levels did not differ. Five patients demonstrated an apparently successful response to dietary treatment with loss of symptoms and glycosuria and fall in post-prandial blood glucose and HbAl. Serum concentrations of thyroid hormones and TBG, however, were not significantly altered. These abnormalities may be unrelated to hyperglycaemia and may reflect the nutritional status of the patients. (Clinical Endocrinology 18 (6)1365-2265)
Xanya Sofra Weiss
A Review of the Biophysical Basis for the Clinical Application of Electric Fields in Soft-Tissue Repair. Xanya Sofra Weiss
Interest in the role of electrical interactions as epigenetic regulators of wound healing had its beginnings nearly 40 years ago, Because the mechanisms of action are not understood (which obviates rational therapy), the empiric application of fields to wounds has produced mixed results. However, taken collectively, clinical trials have demonstrated some beneficial effects. Tests on soft tissues of animals have shown that
electric stimulation can influence the rate of wound healing and scar strength. Natural epithelial-derived sodium currents have been discovered in the wounds of invertebrates and mammals. It is theorized that these currents may be a normal controlling factor in wound healing. Therefore, perturbation of these signals is important to understand. The purpose of this review is to put into proper perspective the biophysical, physiological, and clinical data pertaining to use of electricity to control wound healing, with the goal of minimizing much of the prevailing confusion.
Xanya Sofra Weiss
Friday, March 4, 2011
Can Electrons Act as Antioxidants? A Review and Commentary. Xanya Sofra Weiss
James L. OschmanPh.D; 2007
A previous study demonstrated that connecting the human body to the earth during sleep (earthing) normalizes the daily cortisol rhythm and improves sleep. A variety of other benefits were reported, including reductions in pain and inflammation. Subsequent studies have confirmed these earlier findings and documented virtually immediate physiologic and clinical effects of grounding or earthing the body. It is well established, though not widely known, that the surface of the earth possesses a limitless and continuously renewed supply of free or mobile electrons as a consequence of a global atmospheric electron circuit. Wearing shoes with insulating soles and/or sleeping in beds that are isolated from the electrical ground plane of the earth have disconnected most people from the earth's electrical rhythms and free electrons. The most reasonable hypothesis to explain the beneficial effects of earthing is that a direct earth connection enables both diurnal electrical rhythms and free electrons to flow from the earth to the body. It is proposed that the earth's diurnal electrical rhythms set the biological clocks for hormones that regulate sleep and activity. It is also suggested that free electrons from the earth neutralize the positively charged free radicals that are the hallmark of chronic inflammation. A relationship between cortisol and inflammation was established in the pioneering work of H. Selye published in the 1950s. Current biomedical research has led to an inflammation hypothesis that is establishing chronic inflammation as the culprit behind almost every modern chronic illness. The research summarized here and in subsequent reports provides a basis for a number of earthing technologies that restore and maintain natural electrical contact between the human body and the earth throughout the day and night in situations where going barefoot on the earth is impractical. It is proposed that free or mobile electrons from the earth can resolve chronic inflammation by serving as natural antioxidants.
Xanya Sofra Weiss
The Basis for Micro Current Electrical Therapy in Conventional Medical Practice. Xanya Sofra Weiss
Joseph M. Mercola, Daniel L Kirsch; 1995
The use of electricity in medicine is not new. Clinicians used it over 150 years ago to treat nonunion bone fractures. Electomedicine and nutrition, abandoned early in this century, have been recently revived. Most physicians are unaware of their therapeutic benefits. Electrotherapy, especially micro current electrical therapy (MET) is useful for a variety of clinical conditions. Indeed, it may be the best treatment for many pain-related disorders, providing fast relief of symptoms and quickly promoting healing. It has significantly less side effects than drugs in chronic conditions. The more advanced MET devices can often demonstrate effectiveness with a simple two minute office procedure, allowing validity to be quickly assessed.
Xanya Sofra Weiss
A Novel Collagen. Xanya Sofra Weiss
A novel collagen-binding peptide promotes osteogenic differentiation via Ca2+/calmodulin-dependent protein kinase II/ERK/AP-1 signaling pathway in human bone marrowderived mesenchymal stem cells. Xanya Sofra Weiss
Shin MK, Kim MK, Bae YS, Jo I, Lee SJ, Chung CP, Park YJ, Min do S.
The intracellular signaling events controlling human mesenchymal stem cell (hMSC) differentiation into osteoblasts are poorly understood. Collagen-binding domain is considered an essential component of bone mineralization. In the present study, we investigated the regulatory mechanism of osteoblastic differentiation of hMSC by the peptide with a novel collagen-binding motif derived from osteopontin. The peptide induced influx of extracellular Ca2+ via calcium channels and increased intracellular Ca2+ concentration ([Ca2+]i) independent of both pertussis toxin and phospholipase C, and activated ERK, which was inhibited by Ca2+/calmodulin-dependent protein kinase (CaMKII) antagonist, KN93. The peptide-induced increase of [Ca2+]i is correlated with ERK activation in a various cell types. The peptide stimulated the migration of hMSC but suppressed cell proliferation. Furthermore, the peptide increased the phosphorylation of cAMP-response element-binding protein, leading to a significant increase in the transactivation of cAMP-response element and serum response element. Ultimately, the peptide increased AP-1 transactivation, c-jun expression, and bone mineralization, which are suppressed by KN93. Taken together, these results indicate that the novel collagen-binding peptide promotes osteogenic differentiation via Ca2+/CaMKII/ERK/AP-1 signaling pathway in hMSC, suggesting the potential application in cell therapy for bone regeneration.
Xanya Sofra Weiss
ENERGY MEDICINE AND ANTI-AGING: FROM FUNDAMENTALS TO NEW BREAKTHROUGHS. Xanya Sofra Weiss
After much skepticism, energy medicine and the science behind it are emerging as rich and fascinating topics with major implications for anti-aging medicine. Those who follow this emerging field are being introduced to new vistas about how the human body works in health and disease, and anti-aging specialists are acquiring valuable new tools. The symposium will summarize the fundamentals of energetics and some of the significant breakthroughs. The fundamentals demystify energetics, answer the logical questions raised by skeptics and provide appropriate answers to patient questions. The breakthroughs are revealing how energetic methods are having a dramatic impact on health and longevity, and helping us solve one of the biggest unsolved problems in biology referenced above. We begin by discussing theories of aging to lay a foundation for new concepts based on discoveries in the fields of cell biology and biophysics.
Xanya Sofra Weiss
Nanocurrent for Aesthetics and Anti -Aging. Xanya Sofra Weiss
Xanya Sofra-Weiss
Aging is not just the sum total of individually deteriorating cells, shortened telomeres, denatured proteins and DNA molecules, or oxidative damage in the mitochondria. Aging is the dynamic process of increasing imbalances caused by: (1) cellular energy shortage, (2) incomplete cellular differentiation, (3) immune deficiency, (4) decreased systemic intelligence reflected in a/ defects in repair mechanisms, b/ inadequate spatial orientation and c/ poor network communication. International research has repeatedly shown that: (1)Electrons stabilize free radicals (2) Electron transport within DNA deflects oxidative damage; (3)Electrons provide a) direction information b) embryonic development c) cellular differentiation d) healing.(4) Electron transport chain results in Protons spinning the ATP-synthase in the mitochondria to produce ATP. Additionally, Proteins, the central intelligence mechanism of the cell are synthesized by aminoacids that are bound by virtue of their electric charge. A number of studies have shown that Protein synthesis occurs at specific frequencies below 1 Hz. Modern electronics and molecular biology research are combined to deduce the specifications for a technology that promotes Healthy Anti-aging. Resonating the firings, spatial organization and rhythms of electrically excitable cells leads to healing and rejuvenation in a completely safe, noninvasive method. However, to date, few devices pay attention to waveform formation that reflects the essence of cellular communications. There is a lot to be gained by developing a device that can emit signals capable of intertwining with those of signal transduction receptors (including G proteins, gene transcription and the activation of T cells). Such a device will not only become the protagonist in Anti-aging but it will have sufficient sophistication to heal disease and enhance overall immune efficiency.
Xanya Sofra Weiss
Wednesday, March 2, 2011
Synthesis of Nitric Oxide in Human Osteoblasts in Response to Physiologic Stimulation of Electrotherapy. Xanya Sofra Weiss
Electrotherapy for bone healing, remodeling and wound healing may be mediated by modulation of nitric oxide (NO). Using NO-specific fluorophore (DAF-2), we report here that application of non-invasive, physiologic electrical stimulation induces NO synthesis in human osteoblasts, and that such NO generation is comparable to that induced by estrogen treatment. For example, application of a sinusoidal 1 Hz, 2 V/cm (peak to peak) electrical stimulation (ES) increases NO-bound DAF-2 fluorescence intensity by a 2-fold within 60 min exposure by activating nitric oxide synthase (NOS). Increase in the NO level is found to depend critically on the frequency and strength of ES. While the frequency of 1 Hz ES seems optimal, the ES strength >0.5 V/cm is required to induce significant NO increase, however. Nitric oxide synthesis in response to ES is completely prevented by blocking estrogen receptors using a competitive inhibitor, suggesting that NO generation is likely initiated by activation of estrogen receptors at the cell surface. Based on these findings, physiologic stimulation of electrotherapy appears to represent a potential non-invasive, non-genomic, and novel physical technique that could be used to regulate NO-mediated bone density and facilitate bone remodeling without adverse effects associated with hormone therapy.
Xanya Sofra Weiss
Investigation of human mitochondrial myopathies by phosphorus magnetic resonance spectroscopy. Xanya Sofra Weiss
Dr. D. L. Arnold, MD, D. J. Taylor, DPhil, G. K. Radda, DPhil, FRS; 1984
Abnormal mitochondria are an increasingly recognized cause of neuromuscular disease. We have used phosphorus magnetic resonance spectroscopy to monitor noninvasively the metabolism of high-energy phosphates and the intracellular pH of human skeletal muscle in vivo in 12 patients with mitochondrial myopathy. At rest, an abnormality could be demonstrated in 11 of 12 patients. Ten patients had evidence of a reduced muscle energy state with at least one of the following abnormalities: low phosphorylation potential, low phosphocreatine concentration, high adenosine diphosphate concentration, or high inorganic phosphate concentration. Two patients had abnormal resting muscle intracellular pH. In some patients phosphocreatine concentration decreased to low values during exercise despite limited work output. This was not accompanied by particularly severe intracellular acidosis. Evidence of impaired rephosphorylation of adenosine diphosphate to adenosine triphosphate during recovery from exercise was found in approately half the patients. Phosphorus magnetic resonance spectroscopy is useful in the noninvasive diagnosis of mitochondrial myopathies and in defining the pathophysiological basis of these disorders.
Xanya Sofra Weiss
Counterregulation of beta(2)-adrenoceptor function in human mast cells by stem cell factor. Xanya Sofra Weiss
Mast cells contribute to the pathophysiology of asthma with the sustained release of both preformed and
newly generated mediators in response to allergens and other diverse stimuli. Stem cell factor (SCF) is the key human mast cell growth factor, but also primes mast cells for mediator release. SCF expression is markedly increased in asthmatic airways. Short-acting beta(2)-adrenoceptor drugs such as albuterol inhibit human lung mast cell (HLMC) degranulation in vitro in the absence of SCF, but their effect in the presence of SCF is not known. OBJECTIVE: The aim of this study was to elucidate the effects of albuterol on HLMC function in the presence of SCF. METHODS: Mediator release and K(Ca)3.1 ion channel activity were analyzed in purified HLMC. Intracellular signalling and beta(2)-adrenoceptor phosphorylation and internalization were analyzed in the HMC-1 human mast cell line. RESULTS: beta(2)-Adrenoceptor agonist-dependent inhibition of K(Ca)3.1 ion channels and HLMC mediator release was markedly attenuated in the
presence of SCF. Remarkably, albuterol actually potentiated IgE-induced histamine release in a dose-dependent manner when both SCF and IgE were present. These effects were related to the SCF-dependent phosphorylation of Tyr350 on the beta(2)-adrenoceptor with immediate uncoupling of the receptor followed by receptor internalization. CONCLUSION: The potentially beneficial effects of beta(2)-adrenoceptor agonists in asthmatic airways may be blunted as a result of the high concentrations of SCF present.
Xanya Sofra Weiss
Is Melatonin the Hormonal Missing Link Between Magnetic Field Effects and Human Diseases? Xanya Sofra Weiss
The disruption of melatonin secretion has been largely
studied since it could provide the missing link between the
exposure to 50/60-Hz electric and magnetic fields (EMF) and the
occurrence of possible health effects as the “melatonin
hypothesis”. We analysed the current experimental data from
animal (rodents) where contradictory results have been observed,
and from human studies conducted with volunteers or with
workers in various conditions of exposure, biological endpoints
and metrics. In humans, even in long lasting exposures, the
overall results of these studies do not support the “melatonin
hypothesis”. It is unlikely that malignancies or mood disorders
reported by people exposed to 50/60-Hz EMF could be related to
the disruption of the melatonin levels.
Xanya Sofra Weiss
Live Blood Analysis. Xanya Sofra Weiss
Through a live blood analysis, you can see the life gifting element of your body come alive - your blood. After your health practioner takes one small drop of blood and places it on the slide, you observe as your blood reveals nutritional deficiencies, hormonal imbalances, yeast overgrowths, digestive problems, metal toxicity, liver stress, bacteria and parasite levels. The mysteries of your health become revealed and through the 45 minute assessment provided from your practitioner, you learn how to clean your blood and become an active participant in correcting any areas of concern. In partnership with your practitioner, you establish a proactive nutritional plan that will put you back in control of your own health
Xanya Sofra Weiss
