Background and Purpose. Microamperage direct cuwent and microamperage electromzgnetic stimulation are med to accelerate healing in bone. Although many cliniciaav are wing mimmperage stimulation to relim pain and facilitate wound healing, there is sign@cant question regarding whether this low-intensity direct current sign1fiantly accelerates soft t b wo und repair. The putpose of this study was to determine whether low-voltage pulsed microamperage current (100 p 4 60 V, 0.1 Hz) enhances the healing of supe~jicialf,u ll-thickness, or incisional w o d created to simulate acute abrasions, ulcers, and lacerations. Suttjects. Ten adult Yucatan mini pigs setved as the subjects for this study, Metboa%. Variables associated with healing were measured in 60 matched pairs of surg2'cully induced partial-thick, full-thickmess, and incisionul wouruils after either sham or anodal @irve-polarity) stimulation with pulsed mimmperage cuwent (100 @) was administered for 1 hour per day for 5 days. Sterile, disposable electmdes (2 x4 cm) were placed over each wound, which was kept wrapped and protected throughout the study ResuCis. At 7 days postinjury, all wouruils were healing well with no sgns of infection. There were no dtffermes in tensile strength, collagen density, maturity, or deposition (, ydm.xypline), wound ske, or visual appearance between the sham treatment and treatment lesions. No changes in local subcutaneous oxygen or ternperatue were found in the swine during or afer microamperage stimulation. Codusion and l3ismsdm This study did not provide any evidence to support the use o f microamperage stimulation to accelerate wound healing. No negative effects, however, were f o d . Further research is needed to determine whether there is a cntk:al interaction between the size of the electrode relative to the woud, the density of the current, the duration of the treatment, the polarity of the treatment electrode, and the acuity or chronicity of wounding and the eff~tiveneosf microcurrent stimulation for wound healing. [Byl Nfi Mckvzie AL, West JM, et al. Pulsed microamperage stimulation: a controlled study of healing of surg2'cally induced wound in Yucatan pigs. Pbys Ther.
Xanya Sofra Weiss
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