The clinical application of direct microcurrent (50 to 500 microamperes (uamp) is becoming increasingly popular with the publication of peer review articles on this subject in the scientific literature. Therapeutic application of this modality has enjoyed popularity primarily in the treatment of injuries to soft tissue, as is the case with injuries of athletic origin. This will serve as a review of the mechanism of adenosine triphosphate production relative to direct current application. An artificial proton gradient is formed across the functional membrane, created by acid/base transition, and results in ATP synthesis. This supports the chemiosmotic Theory of Mitchell. During electrostimulation, electrons react with the water molecules at the cathode to produce -OH ions, while protons (H+) are formed at the anode. Accordingly, at the anode/cathode interface, a proton gradient and a potential gradient across the tissue and the medium (cytosol) is created. The net pH of the system remains undisturbed because the rate of proton formation at the anode is equaled by the rate of proton consumption at the cathode.
Xanya Sofra Weiss
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