Monday, June 6, 2011

Synthesis and anti-bacterial, anti-fungal activity of some novel chalcone derivatives. Xanya Sofra Weiss

S.S.Turkar, A.H. Rodge, G.D.Hatnapure, A.P.Keche, G.S.Gaikwad

Department of Chemistry, J.L.Charturvedi College of Engineering, Nagpur- India

Chalcone have displayed an impressive array of biological importance.
A new series of chalcone have been synthesized by reacting 1-(4-isobutylphenyl) ethanone with different substituted aldehyde in turn clasien-schimidt condensation.
All synthesized compounds have been evaluated for anti-bacterial and anti-fungal studies.
Compound 11 showed promising anti-bacterial activities against staphylococcus aureus having MIC50 value of 2.10ug/ml and compound 2 also showed good anti-fungal activity against Candida krusei having MIC50 value of 2.12ug/ml.

Xanya Sofra Weiss

Xanya Sofra Weiss


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