ENERGY MEDICINE AND ANTI-AGING: FROM FUNDAMENTALS TO NEW BREAKTHROUGHS. Xanya Sofra Weiss

After much skepticism, energy medicine and the science behind it are emerging as rich and fascinating topics with major implications for anti-aging medicine. Those who follow this emerging field are being introduced to new vistas about how the human body works in health and disease, and anti-aging specialists are acquiring valuable new tools. The symposium will summarize the fundamentals of energetics and some of the significant breakthroughs. The fundamentals demystify energetics, answer the logical questions raised by skeptics and provide appropriate answers to patient questions. The breakthroughs are revealing how energetic methods are having a dramatic impact on health and longevity, and helping us solve one of the biggest unsolved problems in biology referenced above. We begin by discussing theories of aging to lay a foundation for new concepts based on discoveries in the fields of cell biology and biophysics.

Xanya Sofra Weiss

Xanya Sofra Weiss

Nanocurrent for Aesthetics and Anti -Aging. Xanya Sofra Weiss

Xanya Sofra-Weiss

Aging is not just the sum total of individually deteriorating cells, shortened telomeres, denatured proteins and DNA molecules, or oxidative damage in the mitochondria. Aging is the dynamic process of increasing imbalances caused by: (1) cellular energy shortage, (2) incomplete cellular differentiation, (3) immune deficiency, (4) decreased systemic intelligence reflected in a/ defects in repair mechanisms, b/ inadequate spatial orientation and c/ poor network communication. International research has repeatedly shown that: (1)Electrons stabilize free radicals (2) Electron transport within DNA deflects oxidative damage; (3)Electrons provide a) direction information b) embryonic development c) cellular differentiation d) healing.(4) Electron transport chain results in Protons spinning the ATP-synthase in the mitochondria to produce ATP. Additionally, Proteins, the central intelligence mechanism of the cell are synthesized by aminoacids that are bound by virtue of their electric charge. A number of studies have shown that Protein synthesis occurs at specific frequencies below 1 Hz. Modern electronics and molecular biology research are combined to deduce the specifications for a technology that promotes Healthy Anti-aging. Resonating the firings, spatial organization and rhythms of electrically excitable cells leads to healing and rejuvenation in a completely safe, noninvasive method. However, to date, few devices pay attention to waveform formation that reflects the essence of cellular communications. There is a lot to be gained by developing a device that can emit signals capable of intertwining with those of signal transduction receptors (including G proteins, gene transcription and the activation of T cells). Such a device will not only become the protagonist in Anti-aging but it will have sufficient sophistication to heal disease and enhance overall immune efficiency.

Xanya Sofra Weiss

Xanya Sofra Weiss

Synthesis of Nitric Oxide in Human Osteoblasts in Response to Physiologic Stimulation of Electrotherapy. Xanya Sofra Weiss

Electrotherapy for bone healing, remodeling and wound healing may be mediated by modulation of nitric oxide (NO). Using NO-specific fluorophore (DAF-2), we report here that application of non-invasive, physiologic electrical stimulation induces NO synthesis in human osteoblasts, and that such NO generation is comparable to that induced by estrogen treatment. For example, application of a sinusoidal 1 Hz, 2 V/cm (peak to peak) electrical stimulation (ES) increases NO-bound DAF-2 fluorescence intensity by a 2-fold within 60 min exposure by activating nitric oxide synthase (NOS). Increase in the NO level is found to depend critically on the frequency and strength of ES. While the frequency of 1 Hz ES seems optimal, the ES strength >0.5 V/cm is required to induce significant NO increase, however. Nitric oxide synthesis in response to ES is completely prevented by blocking estrogen receptors using a competitive inhibitor, suggesting that NO generation is likely initiated by activation of estrogen receptors at the cell surface. Based on these findings, physiologic stimulation of electrotherapy appears to represent a potential non-invasive, non-genomic, and novel physical technique that could be used to regulate NO-mediated bone density and facilitate bone remodeling without adverse effects associated with hormone therapy.

Xanya Sofra Weiss

Xanya Sofra Weiss

Investigation of human mitochondrial myopathies by phosphorus magnetic resonance spectroscopy. Xanya Sofra Weiss

Dr. D. L. Arnold, MD, D. J. Taylor, DPhil, G. K. Radda, DPhil, FRS; 1984

Abnormal mitochondria are an increasingly recognized cause of neuromuscular disease. We have used phosphorus magnetic resonance spectroscopy to monitor noninvasively the metabolism of high-energy phosphates and the intracellular pH of human skeletal muscle in vivo in 12 patients with mitochondrial myopathy. At rest, an abnormality could be demonstrated in 11 of 12 patients. Ten patients had evidence of a reduced muscle energy state with at least one of the following abnormalities: low phosphorylation potential, low phosphocreatine concentration, high adenosine diphosphate concentration, or high inorganic phosphate concentration. Two patients had abnormal resting muscle intracellular pH. In some patients phosphocreatine concentration decreased to low values during exercise despite limited work output. This was not accompanied by particularly severe intracellular acidosis. Evidence of impaired rephosphorylation of adenosine diphosphate to adenosine triphosphate during recovery from exercise was found in approately half the patients. Phosphorus magnetic resonance spectroscopy is useful in the noninvasive diagnosis of mitochondrial myopathies and in defining the pathophysiological basis of these disorders.

Xanya Sofra Weiss

Xanya Sofra Weiss

Counterregulation of beta(2)-adrenoceptor function in human mast cells by stem cell factor. Xanya Sofra Weiss

Mast cells contribute to the pathophysiology of asthma with the sustained release of both preformed and
newly generated mediators in response to allergens and other diverse stimuli. Stem cell factor (SCF) is the key human mast cell growth factor, but also primes mast cells for mediator release. SCF expression is markedly increased in asthmatic airways. Short-acting beta(2)-adrenoceptor drugs such as albuterol inhibit human lung mast cell (HLMC) degranulation in vitro in the absence of SCF, but their effect in the presence of SCF is not known. OBJECTIVE: The aim of this study was to elucidate the effects of albuterol on HLMC function in the presence of SCF. METHODS: Mediator release and K(Ca)3.1 ion channel activity were analyzed in purified HLMC. Intracellular signalling and beta(2)-adrenoceptor phosphorylation and internalization were analyzed in the HMC-1 human mast cell line. RESULTS: beta(2)-Adrenoceptor agonist-dependent inhibition of K(Ca)3.1 ion channels and HLMC mediator release was markedly attenuated in the
presence of SCF. Remarkably, albuterol actually potentiated IgE-induced histamine release in a dose-dependent manner when both SCF and IgE were present. These effects were related to the SCF-dependent phosphorylation of Tyr350 on the beta(2)-adrenoceptor with immediate uncoupling of the receptor followed by receptor internalization. CONCLUSION: The potentially beneficial effects of beta(2)-adrenoceptor agonists in asthmatic airways may be blunted as a result of the high concentrations of SCF present.

Xanya Sofra Weiss

Xanya Sofra Weiss

Is Melatonin the Hormonal Missing Link Between Magnetic Field Effects and Human Diseases? Xanya Sofra Weiss

The disruption of melatonin secretion has been largely
studied since it could provide the missing link between the
exposure to 50/60-Hz electric and magnetic fields (EMF) and the
occurrence of possible health effects as the “melatonin
hypothesis”. We analysed the current experimental data from
animal (rodents) where contradictory results have been observed,
and from human studies conducted with volunteers or with
workers in various conditions of exposure, biological endpoints
and metrics. In humans, even in long lasting exposures, the
overall results of these studies do not support the “melatonin
hypothesis”. It is unlikely that malignancies or mood disorders
reported by people exposed to 50/60-Hz EMF could be related to
the disruption of the melatonin levels.

Xanya Sofra Weiss

Xanya Sofra Weiss

Live Blood Analysis. Xanya Sofra Weiss

Through a live blood analysis, you can see the life gifting element of your body come alive - your blood. After your health practioner takes one small drop of blood and places it on the slide, you observe as your blood reveals nutritional deficiencies, hormonal imbalances, yeast overgrowths, digestive problems, metal toxicity, liver stress, bacteria and parasite levels. The mysteries of your health become revealed and through the 45 minute assessment provided from your practitioner, you learn how to clean your blood and become an active participant in correcting any areas of concern. In partnership with your practitioner, you establish a proactive nutritional plan that will put you back in control of your own health

Xanya Sofra Weiss

Xanya Sofra Weiss